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makotoy56/README.md

Makoto Yoshida

Clinical and RWE analytics using EHR data, reproducible workflows, and biomedical research experience.

Role Fit Summary

This portfolio is focused on recruiter review for:

  • Healthcare Data Analytics
  • Clinical Data Analytics
  • Real-World Evidence / RWE
  • Epidemiology / Public Health Analytics
  • Research Data Analytics

Strengths demonstrated across the projects include SQL-based cohort construction, EHR and MIMIC-IV workflows, logistic regression, survival analysis, absolute risk interpretation, SAS/Python validation, Quarto reporting, and reproducible analytics documentation.

Featured Portfolio Projects

Project Best For Methods Tools
COPD ICU RAAS Survival Analysis RWE, clinical data, survival analysis Kaplan-Meier, Cox proportional hazards, sensitivity analysis BigQuery, SQL, Python, SAS, Quarto
Non-ICU RAAS Mortality Analysis Clinical analytics, medication outcomes, absolute risk reporting Logistic regression, marginal effects, sensitivity analysis BigQuery, SQL, Python, SAS, Quarto
Public Health Statistics Workflow Epidemiology, public health analytics Descriptive statistics, age adjustment, regression, forest plots Python, Quarto

Recommended Review Order

  1. COPD ICU RAAS Survival Analysis
  2. Non-ICU RAAS Mortality Analysis
  3. Public Health Statistics Workflow

Review the COPD project first for survival analysis and RWE-style clinical modeling, the non-ICU project second for logistic regression and absolute risk interpretation, and the public health workflow third for epidemiology and population-health statistics.

Skills Demonstrated by Project

COPD ICU RAAS Survival Analysis

  • MIMIC-IV cohort construction
  • BigQuery SQL
  • Kaplan-Meier survival analysis
  • Cox proportional hazards modeling
  • Sensitivity analysis
  • SAS/Python validation
  • Quarto reporting

Non-ICU RAAS Mortality Analysis

  • Non-ICU hospital admission cohort construction
  • Medication exposure definition
  • Multivariable logistic regression
  • Adjusted predicted risk estimation
  • Marginal effects analysis
  • SAS/Python validation
  • Quarto reporting

Public Health Statistics Workflow

  • Descriptive public-health statistics
  • Age-group adjustment
  • Linear regression
  • Logistic regression
  • Forest plot visualization
  • Reproducible reporting

Data Governance and Reproducibility

All clinical projects use de-identified MIMIC-IV data under appropriate PhysioNet access requirements. No patient-level source data, PHI, credentials, or restricted datasets are included in the repositories. Reproducibility documentation is provided through README files, Quarto reports, and REPRODUCIBILITY.md files where applicable.

Technical Stack

  • SQL / BigQuery
  • Python
  • pandas / NumPy
  • statsmodels / lifelines / scikit-learn
  • SAS
  • Quarto
  • Git / GitHub
  • GitHub Pages

Contact

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  1. mimic-iv-copd-raas-analysis mimic-iv-copd-raas-analysis Public

    EHR-based observational survival analysis of ICU patients with COPD using MIMIC-IV. Evaluates the association between pre-ICU RAAS inhibitor exposure and in-hospital mortality using time-to-event m…

    Jupyter Notebook

  2. mimic-iv-nonicu-medication mimic-iv-nonicu-medication Public

    EHR-based observational analysis of adult non-ICU hospital admissions using MIMIC-IV. Evaluates early RAAS inhibitor exposure and in-hospital mortality with multivariable logistic regression, absol…

    Jupyter Notebook

  3. public-health-statistics-workflow public-health-statistics-workflow Public

    Reproducible public health statistics workflow with descriptive epidemiology, age-adjusted regression, forest plots, and Quarto reporting.

    Jupyter Notebook