From 330a8b78694c3824503f30b2499eab43ad5c97e0 Mon Sep 17 00:00:00 2001
From: David Hewitt <mail@davidhewitt.dev>
Date: Thu, 30 Apr 2026 14:13:07 +0100
Subject: [PATCH 1/2] trigger rebuilds when virtualenv changes

---
 pyo3-build-config/src/impl_.rs | 10 ++++++++--
 1 file changed, 8 insertions(+), 2 deletions(-)

diff --git a/pyo3-build-config/src/impl_.rs b/pyo3-build-config/src/impl_.rs
index 3d64cb34e4c..9d6a4666eb5 100644
--- a/pyo3-build-config/src/impl_.rs
+++ b/pyo3-build-config/src/impl_.rs
@@ -1818,10 +1818,16 @@ where
 }
 
 fn venv_interpreter(virtual_env: &OsStr, windows: bool) -> PathBuf {
+    let venv = Path::new(virtual_env);
+    // Rebuild if the virtual environment configuration changes
+    println!(
+        "cargo:rerun-if-changed={}",
+        venv.join("pyvenv.cfg").display()
+    );
     if windows {
-        Path::new(virtual_env).join("Scripts").join("python.exe")
+        venv.join("Scripts").join("python.exe")
     } else {
-        Path::new(virtual_env).join("bin").join("python")
+        venv.join("bin").join("python")
     }
 }
 

From 9b42f6aa71bfff5a1b9510f2d2f765a7ed9091fe Mon Sep 17 00:00:00 2001
From: David Hewitt <mail@davidhewitt.dev>
Date: Thu, 30 Apr 2026 14:29:50 +0100
Subject: [PATCH 2/2] newsfragment

---
 newsfragments/6008.changed.md | 1 +
 1 file changed, 1 insertion(+)
 create mode 100644 newsfragments/6008.changed.md

diff --git a/newsfragments/6008.changed.md b/newsfragments/6008.changed.md
new file mode 100644
index 00000000000..88acca63f4a
--- /dev/null
+++ b/newsfragments/6008.changed.md
@@ -0,0 +1 @@
+`pyo3-ffi` will now rebuild when the Python virtual environment changes in-place.